Dent Neurologic


ADNI4 Trial

The ADNI4 is multi-center, a non-randomized, natural history, non-treatment study. 1,150 participants will be enrolled across three cohorts: cognitively normal (CN), mild cognitive impairment (MCI) and dementia (DEM). Participants between the ages of 55-90 (inclusive) will be enrolled at 59 sites in the United States and Canada. Approximately, 750 participants will be newly enrolled into the ADNI4 study, while 750 participants will be rollover participants, continuing their participation from previous ADNI studies. Clinical/cognitive, imaging, biomarker, and genetic characteristics will be assessed across the three cohorts.

Participants enrolled in the ADNI4 study will undergo longitudinal clinical and cognitive assessments, computerized cognitive batteries, biomarker and genetic tests, PET (amyloid and tau) and MRI scans and cerebral spinal fluid (CSF) collection for up to 5 years.

Inclusion Criteria:

  • The age of 55 – 90 years old
  • Are in good health
  • Have little to no memory concerns or have a diagnosis of early Alzheimer’s disease or Mild Cognitive Impairment (MCI)
  • Have a study partner who can accompany you to all clinic visits

What to Expect:

  • Free Study
  • No Medication Involved

The trial is being run by a team that will include doctors and nurses, and may include other healthcare professionals. This is a free study, and no medication will be involved.

Please contact us today for additional information if you think you, or someone you know, can help us with this important research. You are under no obligation to participate in the trial by contacting us. We look forward to hearing from you soon.

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Want to participate in a study?

Fill out the form below and one of our Research Coordinators will be in contact with you as soon as possible. If we currently do not have a study that is currently available for you, we will add you to our database for future studies.

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